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As a complement to the protein sequence database of PIR and the tertiary structural data bank of Brookhaven, we will present protein biological activity databases. The BAD¡Çs contain information regarding the functional properties of more than 5000 kinds of enzymes. The binding properties of the carrier, inhibitor, or modulator proteins are also included in these databases. In addition, information about wild-type proteins will be presented together with information concerning variant molecules that may be compared under the same analyzing conditions.